Tag: Prostate cancer

Artificial Intelligence in Medicine: Deep Learning in Image-Based Prostate Cancer Diagnosis

Gone are the days of “exploratory surgery.” Today’s magnetic resonance imaging (MRI) is a widely used scanning method that provides accurate 3D pictures of physical anatomy and bodily processes. It is noninvasive, and there is no exposure to radiation as with CT/PET scans. MRI detects changes in atoms under high frequency radio waves within a […] CONTINUE

Prostate Cancer in the Bone? Or Primary Bone Cancer?

The human skeleton is remarkable architecture. It is a framework of bone and cartilage that supports and gives shape to the body. It may be hard to imagine that bones can develop tumors, which are cells multiplying out of control, but it can happen. If it does, most of the time the tumors are benign […] CONTINUE

Bone Marrow: A Magnet for Spreading Cancer Cells

Marrow is a “metastatic niche” Prostate cancer (PCa) and breast cancer (BCa) have some key features in common: When found early and properly treated, survival rates for each are very high Prostate and breast tumors tend to be hormone dependent (androgens for prostate, estrogen for breast) If treatment of the local tumor fails, both cancers […] CONTINUE

Radium-223: A Molecular Smart Bomb for Prostate Cancer Bone Mets

Prostate cancer bone metastasis Roughly 11-12% of men will be diagnosed with prostate cancer (PCa) in their lifetime. Upwards of 20% of treated patients will eventually experience recurrence. One out of 41 PCa patients will die from the disease, since PCa has the ability to metastasize (spread) to distant organs and skeletal sites. In fact, […] CONTINUE

A New Treatment for Painful Bone Mets from Prostate Cancer

Prostate cancer bone metastasis In the U.S., prostate cancer (PCa) is the third leading cause of cancer death among men. It is estimated that about 1 out of 8 men will be diagnosed with PCa, and nearly one in 40 will die from it. If left untreated, prostate cancer tumors will grow, become more aggressive, […] CONTINUE

Gene Loss Provides Important Clue About Prostate Cancer Bone Mets

There are over 20 known lines of prostate cancer (PCa) and some are more able to metastasize (spread) beyond the gland. The majority of PCa cell lines rarely pose a threat to life, especially when diagnosed early. However, the aggressive minority is dangerous. Thanks to today’s ability to map an entire DNA sequence within a […] CONTINUE

Clinical trials test radioimmunotherapy to treat PCa bone mets.

Clinical Trials Test Radioimmunotherapy for Prostate Cancer Bone Mets Prostate cancer is one of the most common forms of bone mets (spread to the bone), along with breast and lung cancer. However, prostate cancer (PCa) has a unique property that allows a new form of targeted tumor destruction called radioimmunotherapy (radiation + an immune system […] CONTINUE

If you have bone mets, peer support can bring comfort.

One of the most discouraging aspects of being diagnosed with cancer that has spread to the bone (bone metastasis or bone mets) is feeling alone. Whether the news comes as a shock because your doctor believed “we got it all out” or you were initially diagnosed with Stage !V disease and therefore expected cancer spread, […] CONTINUE

mpMRI accurately detects significant prostate cancer

Overdetection of Insignificant Prostate Cancer One of the problems with the conventional 12-core TRUS biopsy (transrectal guided ultrasound) has to do with the array of needle placement. It tends to miss cancers in two instances: a) cancers located in the anterior (front) zone of the prostate are easily missed, and b) tumors that have developed […] CONTINUE

Focal laser ablation solves the problem of overtreating prostate cancer

“Stop Overtreating Prostate Cancer!” If the name of Dr. Otis Brawley is not as familiar as Dr. Salk or Dr. Spock, it doesn’t surprise me. It’s not exactly a household word. However, Dr. Brawley holds an important position as the chief medical officer of the American Cancer Society. As a practicing oncologist (specialist in treating […] CONTINUE